Geriatric onset laryngeal paralysis polyneuropathy (GOLPP) is a progressive condition in older, large breed dogs leading to laryngeal paralysis and generalized peripheral neuropathy.

It typically occurs in dogs over 10 years old, with an average onset around 12 years of age. Breeds most commonly affected are:

• Labrador Retrievers

• Golden Retrievers

• Siberian Huskies

• Irish Setters

While the exact causes are unknown, GOLPP involves neuropathy of the recurrent laryngeal nerves causing laryngeal paralysis and dysfunction. Additionally, peripheral nerve damage leads to muscle weakness and mobility impairment.

The main symptoms of GOLPP include:

• changes in bark

• increased respiratory effort

• coughing or gagging

• trouble swallowing

• aspiration pneumonia

Owners may also notice:

• weakness in the hindquarters

• difficulty standing up and walking

• decreased activity tolerance

• fatigue

As neuropathy worsens over time, dogs experience progressive muscle atrophy and worsening mobility. Proper diagnosis involves laryngoscopy to visualize laryngeal paralysis along with diagnostic testing like laryngeal exam, neurologic exam, nerve conduction studies, and muscle biopsies.

Treatment

Treatment for GOLPP focuses on managing symptoms and improving quality of life. Mild cases may only require medication and supportive care. More severe laryngeal paralysis can be treated surgically with procedures like laryngeal tie-back surgery.

Physical rehabilitation is a key component of GOLPP therapy. Rehabilitation helps maintain muscle strength, joint flexibility, and neurological function through modalities like therapeutic exercise, assistive devices, laser therapy, hydrotherapy, and massage. Dogs with GOLPP benefit greatly from a multimodal approach combining rehabilitation, medications, and surgery as needed. Proper treatment allows dogs to live comfortably with GOLPP for many years.